Frequency Of Endometriosis in Females with Infertility Undergoing Diagnostic Laparoscopy : Endometriosis in Females with Infertility

Tahira  Tabbsum; Sehrish  Nafees; Trevor  Hayes; Syed  Mehmood ul Hassan; Abdul  Sattar

doi:10.54393/pjhs.v3i03.65

Authors

Tahira Tabbsum Saint Lukes Hospital Kilkenny, Ireland
Sehrish Nafees University Hospital Cork, Ireland
Trevor Hayes Department of Obstetrician and Gynecologist, Saint Luke’s General Hospital Kilkenny, Ireland
Syed Mehmood ul Hassan Department of Medicine, Services Hospital Lahore, Pakistan
Abdul Sattar Tallaght University Hospital, Ireland

DOI:

https://doi.org/10.54393/pjhs.v3i03.65

Keywords:

Infertility, Endometriosis, Laparoscopy

Abstract

Endometriosis is the most common, chronic condition. Although some females are asymptomatic, the majority of women come with infertility, adnexal mass, or pelvic pain. Endometriosis treatment in the context of infertility poses a variety of challenging clinical issues. Objective: The objective of current study is to identify frequency of endometriosis on laparoscopy in females with infertility. Methods: This retrospective study was done at the Department of Obstetrics and Gynaecology, Saint Luke's General Hospital, Kilkenny, Ireland. Medical records of 215 females meeting the inclusion criteria underwent diagnostic laparoscopy were included. Basic demographical details and clinical examination was evaluated and presented through descriptive statistics. On diagnostic laparoscopy, representative sample was taken and sent to hospital histopathology for evaluation of endometriosis. Chi square test was applied to identify the influence of variables on endometriosis. Results: Mean age of females was 28.67 ± 6.35 years. Mean duration of marriage was 6.63 ± 5.26 years. There were 80 (37.21%) women in which endometriosis was diagnosed. No significant statistical association was seen for endometriosis with age, infertility type and duration of infertility. Conclusions: The findings of this study show an increasing trend in endometriosis identification or occurrence in women with infertility. Endometriosis with infertility is not an uncommon disease in women. Though laparoscopy is intrusive method, but with the right training the issues and complications that come with it can be reduced, which benefits the patients and offers us a clear picture or pathology of the disease

References

Mascarenhas MN, Cheung H, Mathers CD, Stevens GA. Measuring infertility in populations: constructing a standard definition for use with demographic and reproductive health surveys. Population Health Metrics. 2012 Aug; 10(1):17. doi: 10.1186/1478-7954-10-17.

Haider G, Rani S, Talpur S, Zehra N, Munir A. Laparoscopic evaluation of female infertility. Journal of Ayub Medical College Abbottabad. 2010 Mar; 22(1):136-8.

Symons LK, Miller JE, Kay VR, Marks RM, Liblik K, Koti M, et al. The Immunopathophysiology of Endometriosis. Trends in Molecular Medicine. 2018 Sep; 24(9):748-762. doi: 10.1016/j.molmed.2018.07.004.

Haydardedeoglu B, Zeyneloglu HB. The impact of endometriosis on fertility. Women's Health. 2015 Aug; 11(5):619-23. doi: 10.2217/whe.15.48.

Carter JE. Combined hysteroscopic and laparoscopic findings in patients with chronic pelvic pain. The Journal of the American Association of Gynecologic Laparoscopists. 1994 Nov; 2(1):43-7. doi: 10.1016/s1074-3804(05)80830-8.

Mishra VV, Gaddagi RA, Aggarwal R, Choudhary S, Sharma U, Patel U. Prevalence; Characteristics and Management of Endometriosis Amongst Infertile Women: A One Year Retrospective Study. Journal of Clinical and Diagnostic Research. 2015 Jun; 9(6):QC01-3. doi: 10.7860/JCDR/2015/13687.6125.

Khawaja UB, Khawaja AA, Gowani SA, Shoukat S, Ejaz S, Ali FN, et al. Frequency of endometriosis among infertile women and association of clinical signs and symptoms with the laparoscopic staging of endometriosis. Journal of Pakistan Medical Association. 2009 Jan; 59(1):30-4.

Shaheen R, Subhan F, Sultan S, Subhan K, Tahir F. Prevalence of infertility in a cross section of Pakistani population. Pakistan Journal of Zoology. 2010 Aug; 42(4).

Ombelet W, Cooke I, Dyer S, Serour G, Devroey P. Infertility and the provision of infertility medical services in developing countries. Human Reproduction Update. 2008 Dec; 14(6):605-21. doi: 10.1093/humupd/dmn042.

Bulletti C, Coccia ME, Battistoni S, Borini A. Endometriosis and infertility. Journal of Assisted Reproduction and Genetics. 2010 Aug;27(8):441-7. doi: 10.1007/s10815-010-9436-1.

Hummelshoj L, Prentice A, Groothuis P. Update on endometriosis. Women’s Health (Lond). 2006 Jan; 2(1):53-6. doi: 10.2217/17455057.2.1.53.

Tsuji I, Ami K, Miyazaki A, Hujinami N, Hoshiai H. Benefit of diagnostic laparoscopy for patients with unexplained infertility and normal hysterosalpingography findings. The Tohoku Journal of Experimental Medicine. 2009 Sep;219(1):39-42. doi: 10.1620/tjem.219.39.

Aziz N. Laparoscopic evaluation of female factors in infertility. Journal of College of Physicians and Surgeons Pakistan. 2010 Oct; 20(10):649-52. doi: 10.2010/JCPSP.649652.

Chimote A, Samal S, Hariharan C, Angik R. Laparoscopy and hysteroscopy in patients of infertility in a rural set up. International Journal of Reproduction, Contraception, Obstetrics and Gynecology. 2015 Apr 1;4(2):322-9.

Parveen S, Khanam M. Role of combined diagnostic laparoscopy and simultaneous diagnostic hysteroscopy for evaluation of female subfertility factors. Journal Surgery of Pakistan. 2010 Jan; 15(1):44-7.

de Medeiros SF, Yamamoto MM, Galera BB, de Medeiros MA, Barbosa JS. Reassessment of the laparoscopy role in the investigation of infertility and treatment plan determination. Asian Pacific Journal of Reproduction. 2012 Jun; 1(2):93-7.

Hughes EG, Fedorkow DM, Collins JA. A quantitative overview of controlled trials in endometriosis-associated infertility. Fertility and Sterility. 1993 May; 59(5):963-70.

Collins JA, Burrows EA, Wilan AR. The prognosis for live birth among untreated infertile couples. Fertility and Sterility. 1995 Jul; 64(1):22-8.

Holoch KJ, Lessey BA. Endometriosis and infertility. Clinical Obstetrics and Gynecology. 2010 Jun; 53(2):429-38. doi: 10.1097/GRF.0b013e3181db7d71.

Practice Committee of the American Society for Reproductive Medicine. Endometriosis and infertility: a committee opinion. Fertility and Sterility. 2012 Sep; 98(3):591-8. doi: 10.1016/j.fertnstert.2012.05.031.