Demographic, Clinical, and Lifestyle Risk Factors Associated with Lower Gastrointestinal Bleeding: A Cross-Sectional Study at A Tertiary Care Hospital

Demographic Factors Associated with Lower Gastrointestinal Bleeding

Authors

  • Qandeel Jamali Department of Gastroenterology, Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan
  • Nand Lal Seerani Department of Gastroenterology, Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan
  • Atif Ahmed Department of Gastroenterology, Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan
  • Shahzad Ali Jariko Department of Medicine, Bilawal Medical College, Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan
  • Muhammad Kaleem Department of Medicine, Suleman Roshan Medical College, Tando Adam, Pakistan
  • Sheeba Faryal Department of Medicine, Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan

DOI:

https://doi.org/10.54393/pjhs.v6i6.3111

Keywords:

Lower Gastrointestinal Bleeding, Causes, Factors, Internal Hemorrhoids, Rectal Ulcers

Abstract

Gastrointestinal bleeding is classified into upper and lower types; lower GI bleeding occurs distal to the ligament of Treitz, presenting as rectal bleeding with symptoms like fatigue, pallor, or shock. Objectives: To assess the demographic, clinical, and lifestyle risk factors associated with lower gastrointestinal bleeding (LGIB) among patients presenting to a Tertiary Care Hospital, Hyderabad. Methods: This cross-sectional descriptive study was conducted from August 12, 2023, to February 11, 2024, at the Department of Gastroenterology, Liaquat University of Medical and Health Sciences, Jamshoro. A total of 105 male and female patients aged 18–70 years presenting with active rectal bleeding as their main complaint, and the duration of bleeding was not more than 6 months, were included in the study. The biodata of patients, such as age, duration of bleeding, and causes of bleeding, was collected. Results: The Age range of the patients in this study was 18 to 70 years, with a mean age was 42.29 ± 11.64 years. The most common cause of LGIB was internal hemorrhoids 32 (24%) followed by rectal ulcers 12 (9%), ulcerative colitis 10 (7.4%), rectal polyps 9 (6.6%), colitis 8 (5.9%), ileocecal ulcers 4 (2.9%), ileitis and colonic ulcers 3 (2.2%) in patients with Lower Gastrointestinal Bleeding. Conclusions: It was concluded that the most common cause of colorectal bleeding in our patients was carcinomas, while in Western countries, diverticulosis is the commonest cause, and ulcerative colitis is the most common cause in some Eastern countries. Male individuals are more commonly affected by LGIB.

References

Talib MA, Aziz MT, Suleman H, Khosa GK, Joya SJ, Hussain I. Etiologies and outcome of lower gastrointestinal bleeding in patients presenting to a tertiary care Children’s Hospital. Pakistan Journal of Medical Sciences. 2021 Mar; 37(2): 556. doi: 10.12669/pjms.37.2.2676. DOI: https://doi.org/10.12669/pjms.37.2.2676

Jafari SA, Kiani MA, Kianifar HR, Mansooripour M, Heidari E, Khalesi M. Etiology of gastrointestinal bleeding in children referred to pediatric wards of Mashhad hospitals, Iran. Electronic Physician. 2018 Feb; 10(2): 6341. doi: 10.19082/6341. DOI: https://doi.org/10.19082/6341

Menichelli D, Gazzaniga G, Del Sole F, Pani A, Pignatelli P, Pastori D. Acute upper and lower gastrointestinal bleeding management in older people taking or not taking anticoagulants: a literature review. Frontiers in Medicine. 2024 May; 11: 1399429. doi: 10.3389/fmed.2024.1399429. DOI: https://doi.org/10.3389/fmed.2024.1399429

Morkar DN and Hazare S. Spectrum of the causes of lower gastrointestinal bleeding in geriatric patients in tertiary care hospital. Journal of the Scientific Society. 2017 Sep; 44(3): 148-51. doi: 10.4103/jss.JSS_17_16. DOI: https://doi.org/10.4103/jss.JSS_17_16

Padilla BE and Moses W. Lower gastrointestinal bleeding and intussusception. Surgical Clinics. 2017 Feb; 97(1): 173-88. doi: 10.1016/j.suc.2016.08.015. DOI: https://doi.org/10.1016/j.suc.2016.08.015

Aoki T, Hirata Y, Yamada A, Koike K. Initial management for acute lower gastrointestinal bleeding. world Journal of Gastroenterology. 2019 Jan; 25(1): 69. doi: 10.3748/wjg.v25.i1.69. DOI: https://doi.org/10.3748/wjg.v25.i1.69

Peery AF, Crockett SD, Murphy CC, Lund JL, Dellon ES, Williams JL et al. Burden and cost of gastrointestinal, liver, and pancreatic diseases in the United States: update 2018. Gastroenterology. 2019 Jan; 156(1): 254-72. doi: 10.1053/j.gastro.2018.08.063. DOI: https://doi.org/10.1053/j.gastro.2018.08.063

Bhayani P, Natarajan K, Coelho-Prabhu N. Rising Incidence of Inflammatory Bowel Disease in the Asian Subcontinent—An Exploration of Causative Factors. Gastrointestinal Disorders. 2024 Jun; 6(2): 549-56. doi: 10.3390/gidisord6020038. DOI: https://doi.org/10.3390/gidisord6020038

Hussein MS, Alshagawi ZA, Fateel NA, Alashhab HM, Mosleh AM, Almutawa OA et al. Causes and Management of Lower Gastro-Intestinal Bleeding. Journal of Pharmaceutical Research International. 2021 Oct; 33(46A): 629-35. doi: 10.9734/jpri/2021/v33i46A32907. DOI: https://doi.org/10.9734/jpri/2021/v33i46A32907

Ullah HMK, Shafiq M, Ali QM, Ahmed S, Iftikhar A, Anwar Q. Colonoscopic Findings in Patients with Lower Gastrointestinal Symptoms at a Tertiary Care Hospital of South Punjab, Pakistan. Journal of Pakistan Society of Internal Medicine. 2021; 2(1): 47-50. doi: 10.70302/jpsim.v2i1.2113. DOI: https://doi.org/10.70302/jpsim.v2i1.2113

Ali SS, Butt N, Altaf HH, Abbasi A. The Etiology and Outcome of Upper Gastrointestinal Bleeding in Patients Presenting to Tertiary Care Hospital, Karachi. Pakistan Journal of Medical and Health Sciences. 2022 Sep; 16(07): 646-. doi: 10.53350/pjmhs22167646. DOI: https://doi.org/10.53350/pjmhs22167646

Abu Bakar, Khan A, Ishaque R, Talha N, Imran A, Qazi AF. Risk Factors Linked to Gastrointestinal Bleeding Causing Substantial Hematocrit Reduction and Requiring Blood Product Transfusion. Journal of Population Therapeutics and Clinical Pharmacology. 2024; 31(6): 2826–2835. doi: 10.53555/jptcp.v31i6.7108. DOI: https://doi.org/10.53555/jptcp.v31i6.7108

Amin SK, Antunes C. Lower Gastrointestinal Bleeding. [Updated 2021 Jul 19]. Stat-Pearls. Treasure Island (FL): Stat-Pearls Publishing. 2023.

Ullah H, Masood A, Aslam M, Ahmad S, Khan A, Naeem M. Acute upper gastrointestinal bleed: etiological spectrum in a tertiary care hospital of North West region of Pakistan. Journal of Population Therapeutics and Clinical Pharmacology. 2022; 29(2): 393–396.

Zaman Z and Majid Z. Inflammatory bowel disease in Pakistan: Low prevalence or underdiagnosis? World Journal of Gastrointestinal Pharmacology and Therapeutics. 2024 Nov; 15(6): 99226. doi: 10.4292/wjgpt.v15.i6.99226. DOI: https://doi.org/10.4292/wjgpt.v15.i6.99226

Chen X, Xiang X, Xia W, Li X, Wang S, Ye S et al. Evolving trends and burden of inflammatory bowel disease in Asia, 1990–2019: A comprehensive analysis based on the global burden of disease study. Journal of Epidemiology and Global Health. 2023 Dec; 13(4): 725-39. doi: 10.1007/s44197-023-00145-w. DOI: https://doi.org/10.1007/s44197-023-00145-w

Rizvi SB, Lateef F, Mirza T, Hassan S. Clinicopathologic spectrum of colorectal polyps highlighting alarming frequency of pre-neoplastic adenomatous polyps with high grade dysplasia. Rawal Medical Journal. 2024 Aug; 49(3): 539-.

Tai FW and McAlindon ME. Non-steroidal anti-inflammatory drugs and the gastrointestinal tract. Clinical Medicine. 2021 Mar; 21(2): 131-4. doi: 10.7861/clinmed.2021-0039. DOI: https://doi.org/10.7861/clinmed.2021-0039

Lokarjana L, Kanseria T, Roslaeni R, Pratama AY. The relationship between low fiber consumption and the incidence of haemorrhoids patients. 12th Annual Scientific Meeting, Medical Faculty, Universitas Jenderal Achmad Yani, International Symposium on" Emergency Preparedness and Disaster Response during COVID 19 Pandemic"(ASMC 2021)). 2021 Jul:197-199. doi: 10.2991/ahsr.k.210723.047. DOI: https://doi.org/10.2991/ahsr.k.210723.047

Ramos GP and Kane S. Alcohol use in patients with inflammatory bowel disease. Gastroenterology & Hepatology. 2021 May; 17(5): 211.

Downloads

Published

2025-06-30
CITATION
DOI: 10.54393/pjhs.v6i6.3111
Published: 2025-06-30

How to Cite

Jamali, Q., Seerani, N. L., Ahmed, A., Jariko, S. A., Kaleem, M., & Faryal, S. (2025). Demographic, Clinical, and Lifestyle Risk Factors Associated with Lower Gastrointestinal Bleeding: A Cross-Sectional Study at A Tertiary Care Hospital: Demographic Factors Associated with Lower Gastrointestinal Bleeding. Pakistan Journal of Health Sciences, 6(6), 122–126. https://doi.org/10.54393/pjhs.v6i6.3111

Issue

Section

Original Article

Plaudit

Most read articles by the same author(s)