Hyperemesis Gravidarum in the Second Trimester as a Risk Indicator for Preterm Birth: Hyperemesis Gravidarum in the Second Trimester and Preterm Birth

Shumaila Asghar; Mahpara Shaukat; Qaiser Javed

doi:10.54393/pjhs.v6i10.3328

Authors

Shumaila Asghar Department of Gynaecology and Obstetrics, Tehsil Headquarter Hospital, Chichawatni, Pakistan
Mahpara Shaukat Department of Gynaecology and Obstetrics, Sahiwal Medical College, Sahiwal, Pakistan
Qaiser Javed Department of Gynaecology and Obstetrics, Services Institute of Medical Sciences, Lahore, Pakistan

DOI:

https://doi.org/10.54393/pjhs.v6i10.3328

Keywords:

Second Trimester, Hyperemesis Gravidarum, Preterm Birth, Antenatal Care Clinic

Abstract

A severe type of nausea and vomiting during the early stages of pregnancy is called hyperemesis gravidarum. Preterm delivery has been reported to be significantly associated with hyperemesis gravidarum. Objectives: To determine the association between preterm birth and hyperemesis gravidarum in female attending an antenatal care clinic in the second trimester. Methods: This Cohort1study was carried out at the Department of Obstetrics and Gynaecology, Sahiwal Teaching Hospital, Sahiwal. A total of 200 female were enrolled and divided into two groups with and without hyperemesis gravidarum. Then female were followed up in OPD until delivery. If female had a delivery before 37 weeks of gestation, then preterm birth was labelled. Data were analyzed in SPSS version 23.0. Results: The mean age of the female was 31.25 ± 5.98 years. In our study, 40 (40%) female were primigravida. The mean gestational age at presentation was 17.47 ± 3.51 weeks, while at delivery it was 37.27 ± 1.94 weeks. In the exposed group, preterm birth was noted in 45 (45%) cases, while in the unexposed group, preterm birth was noted in 15% cases. Thus, there was 1.909 times more risk of preterm birth in females with hyperemesis gravidarum as compared with female without hyperemesis gravidarum, i.e., RR=1.909 (95% CI; 1.483, 2.457, p<0.001). Conclusions: There is more than about two times greater risk of preterm birth in female with hyperemesis gravidarum during the second trimester of their pregnancy.

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